The Ultimate Guide to Cleaning Frames and Glass Safely: Protecting Your Art Without Risk

Why Cleaning Matters More Than You Think

Have you ever caught yourself wiping down your framed art with a quick swipe of a paper towel or spritzing it with glass cleaner? You’re not alone—we all want our art to shine and look its best. But here’s the thing: even the simplest cleaning mistake can lead to permanent damage. Smudges, dust, and fingerprints might seem harmless, but if you use the wrong materials or techniques, you could be putting your artwork at risk. Imagine accidentally pushing moisture through the frame or scratching the glass that protects your treasured print. Scary thought, right? 

At The Frame Shop, we’ve seen all kinds of damage caused by well-meaning but improper cleaning attempts. That’s why we’re here to talk about the right way to clean your frames and glass—so you can preserve your artwork safely while keeping everything looking gorgeous. Whether you’re dusting a family portrait, cleaning a high-end print, or sprucing up your gallery wall, you need to know the dos and don’ts of safe cleaning. Let’s dive into the smart, simple steps that will keep your frames spotless and your artwork unharmed.

Understanding the Risks: Why You Can’t Just Wipe and Go

Before we talk tools and techniques, let’s look at the risks of cleaning framed artwork without care. You might be thinking: how much damage can a little spray and wipe really do? The truth is—a lot. Liquid can seep into frame edges and reach the artwork inside, especially if it’s mounted close to the glass. 

Over time, this can cause discoloration, mildew, and even ink or pigment bleeding. Plus, using harsh glass cleaners, like those containing ammonia or alcohol, can leave behind residues that etch or cloud the surface, particularly on acrylic glazing. And that microfiber cloth you grabbed? It might actually scratch your anti-reflective glass if it’s been used elsewhere and picked up debris. We had one client bring in a limited-edition print that looked foggy and dull—the culprit? 

Years of using regular window cleaner. Cleaning may seem like a mundane chore, but when it comes to framed art, it deserves just as much care as the piece itself. Ask yourself: When was the last time you cleaned your frames? What did you use? How did you do it? If you’re unsure, you’re in the right place. Let’s walk through exactly how to avoid common pitfalls and clean smartly.

Choosing the Right Tools for the Job

Let’s start with your toolkit. What should you actually use to clean frames and glass safely? Here’s a hint: ditch the paper towels and all-purpose sprays. Instead, reach for a few essential items: a soft microfiber cloth (ideally one that hasn’t been used for anything else), a blower or soft-bristled brush for dust removal, distilled water in a spray bottle, and if needed, a gentle, ammonia-free glass cleaner designed for artwork or electronics. If your frame includes acrylic (plexiglass) rather than glass, you’ll want to be even more careful.

Acrylic scratches easily and can become cloudy if cleaned with the wrong chemicals. Use a specialized plastic cleaner or a diluted mix of mild soap and distilled water. And don’t forget gloves! Clean cotton or nitrile gloves can prevent fingerprints or oil transfer when handling the frame or glass. 

At The Frame Shop, we use a two-step process: first, dry cleaning with a microfiber cloth or brush to remove surface dust, then a careful damp clean when necessary. No dripping, no direct sprays on the surface. Ever. Sound intense? It’s not! Once you have the right tools and habits, it becomes second nature. Have a favorite cleaner at home? Check its label for ammonia or alcohol. If it contains either, set it aside for your windows, not your art.

Tackling Dust Without Damage

Dust may seem harmless, but it can be abrasive, and if left to accumulate, it can work its way into frame crevices or dull the appearance of glass and mats. So, what’s the best way to remove dust without harming your piece? The safest route is to start with a soft, dry microfiber cloth and a gentle hand. Avoid circular rubbing—that can create micro-abrasions. 

Instead, use light, straight strokes from top to bottom. For ornate or carved frames, a clean, dry artist's brush or a camera lens blower can get into nooks and crannies without scratching. Never use feather dusters, as they can scatter particles or even catch on delicate frame details. One client we worked with used a vacuum—and ended up dislodging a corner of their antique frame! If your frame is especially valuable or fragile, consider bringing it to a professional (like us!) for deep cleaning. Ask yourself: when was the last time your art was dusted carefully? 

Does it have intricate edges that trap dirt? Take a moment to examine your frames and try this gentle method today. A little mindful dusting goes a long way toward long-term preservation.

Safe Techniques for Cleaning Glass Without Touching the Art

Now, let’s get down to glass cleaning. This is where most accidental damage occurs. The number one rule? Never spray cleaner directly on the glass. Instead, lightly mist your microfiber cloth and then wipe the surface in smooth, vertical strokes. That way, you avoid overspray that could seep into the frame. If the artwork is mounted tightly under the glass or doesn’t have spacers, it’s even more important to use a minimal amount of moisture. When dealing with acrylic glazing, apply the same method but use an appropriate plastic cleaner. 

Another tip: use two cloths—one for cleaning and a dry one to buff. We recommend working in good lighting so you can catch smudges and avoid pressing too hard. One of our clients was horrified to discover a foggy patch on their UV acrylic after using a glass cleaner with ammonia. We helped restore clarity using a plastic polish, but not all materials are that forgiving. So, next time you go to wipe your frame, stop and ask: Am I spraying the cleaner directly? Is this the right cleaner for the glazing type? Being mindful makes all the difference.

Frame Cleaning by Material Type: Wood, Metal, and More

Not all frames are made equal, and cleaning methods should depend on the frame's material. For wood frames, especially those with finishes or patinas, avoid moisture. Use a dry microfiber cloth or soft brush to gently wipe down the surface. A slightly damp cloth (with distilled water only) may be used on sealed wood finishes—but always test a small area first. For metal frames, check for signs of corrosion or finish wear. You can clean with a barely damp cloth, then buff with a dry cloth. Avoid harsh polishes or abrasive cleaners. 

For composite or resin frames, stick to soft cloths and gentle wiping. Never scrape off gunk with your fingernail or any hard object—you risk scratching or chipping the surface. A client once used an old toothbrush on a painted resin frame and ended up removing paint in the process. Don’t let that happen to you! Always ask: What is my frame made of? Is it painted, varnished, or raw? Tailor your approach to the material, and when in doubt, less is more.

When to Say "Stop!" and Call in the Pros

Sometimes, it’s best to step back and call in a professional—especially if you notice any of the following: fogging or separation between the glass and the artwork, mold or mildew spots, signs of water damage, or frames that are coming apart at the corners. If you’re dealing with an antique or heirloom piece, any cleaning effort could pose a risk. One of our regular clients brought in a vintage photograph where moisture had wicked through the mat from repeated over-spraying. 

We carefully disassembled the frame, dried the components, and re-framed the piece with museum-quality materials. If you’re unsure whether it’s safe to clean your frame or glass, the safest bet is to ask. We offer evaluations and gentle cleaning services that ensure your artwork stays safe and beautiful. Think of us as your art’s best friend in times of need. Next time you pause with cloth in hand, ask: Is this job too big for DIY? Is there damage I don’t fully understand? If so, give us a call. We’re here to help.

Maintenance Schedules: How Often Should You Clean?

So, how often should you clean your framed artwork? The answer depends on your home environment. If your home is dust-prone or near high-traffic areas like hallways or living rooms, a gentle dusting every few weeks is a good routine. Deeper cleaning of the glass and frame can be done every few months. Avoid over-cleaning—frequent contact increases the risk of damage. 

One client had a routine of cleaning weekly, but after noticing faint scratches on the acrylic, we advised spacing it out and using softer cloths. Consider setting a quarterly reminder to do a full visual inspection of your framed pieces. Look for dust buildup, moisture spots, or signs of frame separation. If you’re rotating art seasonally, that’s also a great time to do maintenance cleaning. 

Ask yourself: Do I have a cleaning schedule? Is it too often or not enough? Just like your furniture or floors, your frames need attention, but with a gentler touch.

Creating a Safe Display Environment

Beyond cleaning, prevention is the best protection. Think about where your artwork is displayed. Avoid areas prone to cooking steam, bathroom humidity, or direct sunlight (which we’ve covered in another guide!). 

Consider installing UV-filtering glass, using proper spacers in framing, and opting for sealed backs to reduce dust intrusion. Make sure your art is hung securely to avoid vibration or movement that can attract dust and allow particles to settle in the corners. We worked with a client who relocated their entire gallery wall from above a heat vent—they were amazed at how much less dust accumulated afterward. 

Ask yourself: Is your art near a vent, window, or kitchen? What’s the air circulation like in that room? Making smart placement choices reduces the need for frequent cleaning and supports long-term preservation.

Care for Your Art Like a Pro!

You made it to the end—and now you’re ready to clean your artwork the right way! It might feel like a lot, but these steps quickly become habits. Start by checking your current cleaning tools and replacing anything abrasive or chemical-heavy. Review where your art hangs and whether it’s exposed to extra dust or sunlight. And remember: gentle, consistent care is the key to long-lasting beauty. 

At The Frame Shop, we love helping our clients preserve their artwork, not just frame it. If you ever feel unsure, reach out. We’re happy to give advice, provide professional cleaning, or reframe with materials that help reduce dust and light exposure. 

So next time you pick up that cloth, ask: Am I protecting or risking my art? 

With a little knowledge and the right tools, you can confidently say, "I’ve got this." 

Happy cleaning!